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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA5
All Species:
30.61
Human Site:
S144
Identified Species:
44.89
UniProt:
O75582
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75582
NP_004746.2
802
89865
S144
G
E
L
F
T
H
L
S
Q
R
E
R
F
T
E
Chimpanzee
Pan troglodytes
XP_001140389
894
100719
S236
G
E
L
F
T
H
L
S
Q
R
E
R
F
T
E
Rhesus Macaque
Macaca mulatta
XP_001088246
1054
117436
S402
G
E
L
F
T
H
L
S
Q
R
E
R
F
T
E
Dog
Lupus familis
XP_547953
806
90703
S151
G
E
L
F
T
H
L
S
Q
R
E
R
F
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
H151
E
I
V
L
A
L
E
H
L
H
K
L
G
I
I
Rat
Rattus norvegicus
Q63531
735
82865
S154
G
D
L
F
T
R
L
S
K
E
V
M
F
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
D140
T
I
E
Y
M
A
P
D
I
V
R
G
G
D
T
Chicken
Gallus gallus
Q5F3L1
789
89022
H159
V
L
A
L
E
H
L
H
K
L
G
I
I
Y
R
Frog
Xenopus laevis
P10665
733
82620
S154
G
D
L
F
T
R
L
S
K
E
V
M
F
T
E
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
S159
G
D
V
F
T
R
L
S
K
E
V
M
F
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
Y356
G
E
L
F
T
H
L
Y
H
S
E
N
F
E
E
Honey Bee
Apis mellifera
XP_395099
910
102507
Y159
G
E
L
F
T
H
L
Y
Q
R
E
H
F
T
E
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
K147
K
V
I
Y
R
D
L
K
L
E
N
I
L
L
D
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
L145
I
K
L
E
N
I
L
L
D
K
D
G
H
V
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
K125
T
V
K
V
Y
S
G
K
D
F
T
L
P
F
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
75
93.1
N.A.
62.8
41
N.A.
82.1
89.4
40
40.5
N.A.
28.5
45.7
46.8
53.3
Protein Similarity:
100
88.5
75.1
95.1
N.A.
76.6
57.9
N.A.
86.1
94.6
57.4
57.3
N.A.
40
62.3
63
66.2
P-Site Identity:
100
100
100
100
N.A.
0
60
N.A.
0
13.3
60
53.3
N.A.
66.6
86.6
6.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
13.3
73.3
N.A.
6.6
20
73.3
73.3
N.A.
66.6
86.6
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.2
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
7
7
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
19
0
0
0
7
0
7
13
0
7
0
0
7
7
% D
% Glu:
7
38
7
7
7
0
7
0
0
25
38
0
0
7
57
% E
% Phe:
0
0
0
57
0
0
0
0
0
7
0
0
57
7
0
% F
% Gly:
57
0
0
0
0
0
7
0
0
0
7
13
13
0
0
% G
% His:
0
0
0
0
0
44
0
13
7
7
0
7
7
0
0
% H
% Ile:
7
13
7
0
0
7
0
0
7
0
0
13
7
7
7
% I
% Lys:
7
7
7
0
0
0
0
13
25
7
7
0
0
0
0
% K
% Leu:
0
7
57
13
0
7
75
7
13
7
0
13
7
7
0
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
19
0
0
0
% M
% Asn:
0
0
0
0
7
0
0
0
0
0
7
7
0
0
0
% N
% Pro:
0
0
0
0
0
0
7
0
0
0
0
0
7
0
7
% P
% Gln:
0
0
0
0
0
0
0
0
32
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
7
19
0
0
0
32
7
25
0
0
7
% R
% Ser:
0
0
0
0
0
7
0
44
0
7
0
0
0
0
0
% S
% Thr:
13
0
0
0
57
0
0
0
0
0
7
0
0
50
7
% T
% Val:
7
13
13
7
0
0
0
0
0
7
19
0
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
13
7
0
0
13
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _